Owen Farrell will captain England during their Guinness Six Nations opener against Ireland after Eddie Jones unveiled his 35-man squad to prepare for the 2019 Championship.
Injury rules out Dylan Hartley who was co-captain alongside Farrell in the autumn series.
Mako and Billy Vunipola and Joe Launchbury make their returns to the squad after missing the Autumn Internationals
There are also recalls for Dan Cole, Jack Clifford and Ollie Devoto while the uncapped names included are Ollie Thorley, Ben Earl, Jack Singleton and Dan Robson – the latter the only No.9 named alongside Ben Youngs in the 35-strong party.
“We are very happy with the squad and have a number of players who have come back from long-term injury.
Eddie Jones
“We are looking forward to getting across to Portugal and having a good ten-day preparation for the Ireland game.”
England squad for Ireland Test:
Forwards
Jack Clifford (Harlequins)
Dan Cole (Leicester Tigers)
Luke Cowan-Dickie (Exeter Chiefs)
Tom Curry (Sale Sharks)
Ben Earl (Saracens) *
Ellis Genge (Leicester Tigers)
Jamie George (Saracens)
Nathan Hughes (Wasps)
Maro Itoje (Saracens)
George Kruis (Saracens)
Joe Launchbury (Wasps)
Courtney Lawes (Northampton Saints)
Ben Moon (Exeter Chiefs)
Brad Shields (Wasps)
Kyle Sinckler (Harlequins)
Jack Singleton (Worcester Warriors) *
Billy Vunipola (Saracens)
Mako Vunipola (Saracens)
Harry Williams (Exeter Chiefs)
Mark Wilson (Newcastle Falcons)
Backs
Chris Ashton (Sale Sharks)
Mike Brown (Harlequins)
Joe Cokanasiga (Bath Rugby)
Elliot Daly (Wasps)
Ollie Devoto (Exeter Chiefs)
Owen Farrell (Saracens) captain
George Ford (Leicester Tigers)
Jonny May (Leicester Tigers)
Jack Nowell (Exeter Chiefs)
Dan Robson (Wasps) *
Henry Slade (Exeter Chiefs)
Ben Te’o (Worcester Warriors)
Ollie Thorley (Gloucester Rugby) *
Manu Tuilagi (Leicester Tigers)
Ben Youngs (Leicester Tigers)
*Uncapped
Players unavailable due to injury
Piers Francis (Northampton Saints)
Dylan Hartley (Northampton Saints)
Jonathan Joseph (Bath Rugby)
Chris Robshaw (Harlequins)
Sam Underhill (Bath Rugby)
Anthony Watson (Bath Rugby)